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Epclusa User Reviews & Ratings (Page 4)

Epclusa has an average rating of 7.7 out of 10 from a total of 381 reviews on Drugs.com. 66% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Epclusa

  • Light...
  • Taken for 1 to 6 months
  • May 23, 2019

For Hepatitis C "I completed Epclusa treatment in August 2018 and was cleared hep c free in September. During treatment I didn't have any major physical side affects except for tinnitus but I was very moody, depressed, short tempered and had anxiety. 9 months on I still have tinnitus but that's the least of my worries. I have allergies which I never had before and I am always sick now. I now have leaky gut syndrome and have some food intolerances. The most challenging thing is having depression and anxiety. Some days I feel a burst of sadness & depression where I would be affected the entire day and it has become frequent but I'm lucky to have a very supportive partner who's there for me. I have absolutely nothing to be depressed about but I get these feelings. I refuse to fall victim in taking big pharmas antidepressants. Epclusa has maybe saved my life which I am very grateful but I am annoyed that its priced at 80k for treatment! I no longer have hep c but it did come at a price. Time to detox."

7 / 10
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  • cory...
  • Taken for 1 to 6 months
  • February 21, 2024

For Hepatitis C "Hi, I'm on my last month of Epclusa and I thought I was the only one to experience these severe side effects! Since I started taking the medication, I itch like crazy and now have a rash on my leg. The stomach issues, forget about it, and the headaches, I've never had such bad headaches in my whole life. The fatigue and tiredness are unreal; my boss has had to take me home because my body would just not do anything! So, as for having hep C is uncanny, let alone having to deal with it. I would not recommend this drug by any means, especially if you have other issues with your liver and or other organs already."

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  • Treat...
  • Taken for 1 to 6 months
  • July 29, 2018

For Hepatitis C "Finished my 12 week treatment 4 days ago on the 25 July 2018, No side effects the whole treatment, in fact I have never felt so good. This morning I woke up feeling really sore, aching and tired but not sick, grumpy and irritable. I didn’t realise there maybe some form of withdrawals from the medication but it makes sense. I have stayed healthy, worked no less than 4 times a week since starting treatment. Today I feel exhausted, horrible and depressed. I'm hoping this feeling goes away. I will update in a week or so. I’m still saying 10/10 because I’m so thankful to have been able to use this medication"

10 / 10
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Frequently asked questions

  • alimony
  • May 13, 2017

For Hepatitis C "I take my last pill tomorrow. My arm, around the elbow is hurting real bad. Real, real bad. I felt it about a week into it. I did my 6 week blood test and no sign of the hep c. I hope it stays that way. I'm not sure of my level? 3-4-5? I forgot.. It messed with my memory too. Feel confused and not sure of myself. Nothing worse when 500 craft personnel depend on you. I just turned 58. Had this for 20 years is my guess.. I haven't drank alcohol in 3 months. I hope you folks who are starting the program don't either. Never had headaches or diarrhea like everyone says. My arm is killing me. Can hardly do anything with it.. I hope this rids this terrible virus. I wish the best for everyone."

5 / 10
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  • Fran
  • Taken for 1 to 6 months
  • July 26, 2018

For Hepatitis C "I’m 61 and I’ve had Hep c for over 30 years. My viral load was almost 2 million. It went down to 0 within my first month with no negative side effects and my enzymes are normal. I’ve got 8 more weeks to go. Hope it stays away forever... God Bless!"

10 / 10
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Are you taking this medicine?

  • Hep...
  • Taken for 1 to 6 months
  • January 27, 2019

For Hepatitis C "I took Epclusa for 12 weeks. The first few weeks I didn't have many side effects. After about a month I started having a lot of weird dreams and not sleeping well. Began having fatigue and brain fog. I thought I was going to get through the 12 weeks with somewhat mild side effects. About the tenth week I started having severe fatigue, severe memory issues (brain fog). I could not wait to get through the last three weeks. It almost had me demobilized."

9 / 10
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  • Hopef...
  • April 25, 2019

For Hepatitis C "Finished my last dose of Epclusa on March 15 , and was weak but a month later I am soo tired and weak it's hard to do anything. I feel like all of my energy has been sucked from my body! I am completely miserable! I'm worried and wondering if anyone else has these symptoms? Literally in bed 24/7!"

1 / 10
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34 Report

More FAQ

  • Anonymous
  • October 19, 2018

For Hepatitis C "I had hep c, genotype 3 for years with my viral load over 6 million. I took this med for 30 days with very minimal side effects over a year ago. I’m extremely proud to say it worked! I’m cured! I just did a blood test. I can’t say enough good things about this drug! It truly saves lives. Good luck on your journey. I hope it does the same for everyone that needs it."

10 / 10
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  • RJano
  • Taken for 1 to 6 months
  • December 13, 2018

For Hepatitis C "Shared my story a few weeks ago. Received my results this week ahead of appt. with Dr. and feel blessed that HVC was undetectable one month out and liver enzymes were normal after being elevated for 25 plus years. Hope to be virus free after 90 days as is the standard. Good luck to everyone and stick with it."

10 / 10
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  • Chaz
  • Taken for 6 months to 1 year
  • June 30, 2018

For Hepatitis C "After living with Hep C genotype 3 for 25 years and at the age of 66 , I was put on Epclusa for 12 weeks. After 1 month, there was no trace of the virus. I continued to take it until the last dose. I did have side effects the worst being stomach aches, ringing in my ears, and extreme irritability. It has been one year after my treatment and the virus is undetected. Epclusa literally saved my life. I was in Stage one liver cirrhosis and I was very ill all of the time. I feel so much better now. One side effect that seems to be permanent is the ringing in the ears."

10 / 10
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  • Hope
  • Taken for 1 to 6 months
  • June 18, 2018

For Hepatitis C "I'm a 34 year old women healthy other then hep c. I got hep c from a blood transfusion when I was a baby. AST & ALT have always fluctuated and have been elevated. Fibro score (estimate of scarring in liver) was f1-f2 Also I was geno type 3. I never even take Advil so I was very scared to use this drug. Side effects was ringing in my ears, teeth sensitivity and not headache but like a weird head change. Nothing major and I felt very normal otherwise. I took the pill right before I went to sleep at night. Never missed a pill.After first month viral load not detected after 6 months still not detected so I am cured. And all AST & ALT are now normal. My fibro score stayed the same after 3 months but I was told my liver is still healing and your liver does heal. So I will give it more time and with the help of herbs and vitamins. Ear ringing went away but still happens occasionally. I hope everyone can be cured of this disease. We will win this battle."

10 / 10
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  • Grate...
  • Taken for 1 to 6 months
  • September 15, 2018

For Hepatitis C "I have had Genotype 2 for over 50 years w/o knowing it! My viral load was 12 million/ML. Had several blood transfusions in 1964/1965. I have been on EPCLUSA since Aug 14th. First blood test Sep 12th, and the virus can no longer be detected! I am so grateful and happy right now!!! Someone here said to drink lots of water, so I drink at least 100 oz/day. Thank you Gilead, for developing this drug, and thank you Drugs.com for creating this review site! I read everyone's review before starting EPCLUSA, and it helped to know what to look for!"

10 / 10
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  • Texas
  • October 14, 2019

For Hepatitis C "I was diagnosed with Hep C geno 3 in April 2019 after I had symptoms of always being tired and my body felt sluggish all the time. I got the virus from donated blood back in 91 when I had my last surgery. I was scared when I found out cause I have kids and I friends who’s parents passed from Hep C. My biopsy came back great and I’ve been taking Epclusa for a month now. I’ve had some headaches but I think the weather changing plays a part cause it goes away. Other than that no problems and I feel great. I have more energy, increased appetite, sleep better and just thankful for this medication. I was nervous but Epclusa is worth it. I had my kids tested even though the % is low there’s still that chance and my youngest who’s 11 came back positive. I had complications during my pregnancy (complete placenta Pre-via) with her. She has been so strong through this process and I answer any questions she has. We are waiting for her to be approved for treatment by next month."

10 / 10
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  • Tano
  • Taken for less than 1 month
  • April 15, 2021

For Hepatitis C "I found out in December 2020 that I have hep C - I know I had to have gotten it within the past 3 to 4 years! I just started taking Epclusa yesterday on 4/13/21. I decided to start taking it in the middle of the afternoon in case the side effects were bad. Last night about 8 or 9 hours after taking it I started feeling pain on the inside of my ankle joints and felt my feet start feeling tingly - it would be ok while walking around but the moment I sat or laid down I started feeling it . It helped to elevate my feet. I didn't have that feeling this morning but a few hours after taking it the feeling started happening again and this time I am also getting the pain in my left elbow joint. I hope and pray that it doesn't get worse but I am expecting to feel worse before I feel better ! I hope and pray everyone with hep C can get through treatment , be cured and never get it again! I will update again if side effects worsen."

10 / 10
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  • Disap...
  • August 5, 2019

For Hepatitis C "I have been on Epclusa for 3 weeks and so am experiencing negative effects; headache, chills, earache, muscle aches, numbing in hands and feet, diarrhea, sores on hands and mouth. I’m also anemic and one of the side effects is anemia. Sometimes I wonder if the Dr did any homework before putting me on this medication. Unfortunately I’ve had to do my own so I hope this helps anyone who is suffering the way I am. I will definitely stop this medication before it does more damage to me"

1 / 10
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  • 3aano
  • January 25, 2017

For Hepatitis C "I have had hep C for about 20 years now, genotype 3a. I already did my 3 month treatment of Epclusa. At end of 3 months, the virus was undetectedable, of course. Waiting to get blood work in March to find out if still undetected. My main side effect of Epclusa was major muscle aches. My muscles were always very stiff and sore. Totally manageable though. I was hoping after I finished treatment, it would go away..,but unfortunately it has not. Some days are worse than others...hoping time will make it go away. Praying and hoping will be undetected and cured still in March. Good luck and God bless to all struggling."

8 / 10
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  • Jacobem
  • July 25, 2018

For Hepatitis C "My husband is on day 55 of Epclusa. He has done fantastic so far! Levels have lowered, soon hopefully gone, and has had minimal issues, and no serious issues that has prevented him from working (he does concrete and physical labor in 100+ degrees daily) he has had some headaches, and the further on he goes, the worse his bone and joint pain gets, but again, not debilitating. He looks at the brighter side daily and having a positive attitude is the key to tolerating the aches and pains that comes along. He has had dizzy spells, so we increase his water intake, and it makes it better. No other medications were tried prior to this, so I can't speak for them, but I can say that Epclusa has definitely been a liver saver! It also takes a lot for your significant other to be a part of this, speaking personally, and dealing with the irritability and mood changes.. but I also, look at the brighter side, and stay optimistic. A good attitude is needed for all involved!"

10 / 10
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  • Anonymous
  • March 5, 2021

For Hepatitis C "I am a 46-year old woman, and I have had Hep C genotype 4A for 29 years, with thankfully very little liver damage so far (it probably helps that I quit drinking 25 years ago). Tonight is my sixth night since starting the Epclusa—I had bizarrely dry lips the first two days despite drinking copious amounts of water (so dry they sort of tingled), but that seems to have passed. My main side effects so far are terribly raging mood swings and tiredness. But also I have a 16 month old toddler and we are living in a pandemic and I work a pretty taxing job so... who knows! I also just got a Covid vaccine three days ago, and there is definitely no data whether that might also be contributing. No other side effects so far, which is great because I was very worried about headaches and nausea. Feeling very grateful we all get to try this rather than the horrors of interferon. Will report back whether anything changes with the moodiness/fatigue."

5 / 10
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  • Blange...
  • Taken for less than 1 month
  • July 28, 2019

For Hepatitis C "On my 8th day now. I get what everyone says about the brain fog and few mild headaches, but it is manageable. If it stays like it has then it's well worth the feeling bit rough for a while - I think. Good luck anyone else who's on Epclusa. I hope it works for you all"

7 / 10
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  • Ray...
  • March 30, 2017

For Hepatitis C "I took it for 12 weeks, when I did the blood work it came back neg..no virus. Boy I was the happiest man on earth, now I have a chance to see my grand babies grow. Went back for my 3 month check up and found out it came back! What a hart breaker. Not sure what to do next..was told another drug would be available this summer "

1 / 10
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  • Joe
  • Taken for 1 to 6 months
  • March 29, 2022

For Hepatitis C "I took Epclusa from 1-6-18 thru 4-6-18 and had no problems the first 2 months but on the last month I started feeling jaw pain, arthritis in hands and feet as well as kidney pain. Within 5-6 months I had developed kidney stones, lost 8 teeth and got bells palsy. For me my condition has worsened. The army Drs say no way Epclusa could have done this. My conditions now include chronic kidney disease, auto immune disease, arthritis. All of this happened after lab tests were normal other than hep c. Conditions as of 3-29-22 have worsened. Every little cold is life threatening. I would advise against taking this medicine."

3 / 10
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  • Carole
  • March 12, 2020

For Hepatitis C "I have genotype 1B (whatever that means) of Hep C I'm 63 years young and found out 28 yrs. ago that I had Hep C. I've been on the treatment for 12 days. I've had some nausea along with some diarrhea. The worse part is fatigue, brain fog, (big time), or is it depression. I do suffer from situational depression so it could be that. Loss of appetite and weakness and very dry mouth. It's been such a short while and I'm afraid of what's to come."

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  • alex...
  • Taken for 1 to 6 months
  • June 1, 2021

For Hepatitis C "I do not usually google side effects etc for fear of psychosomatic symptoms, but after 6 weeks on the drug I am losing my mind. It is a relief to read these reviews. Headaches (when I rarely had them prior) absolutely no energy. Weight loss - The nightmare begins when I try to sleep - sleep? LOL - massive insomnia. My feet and hands tingle resulting in my having to walk around. The tingling disappears when I move. Anxiety, Depression, unable to focus - I am on my way to secure a valium script :("

1 / 10
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  • KQTmom
  • July 20, 2017

For Hepatitis C "I have 10 days left on my Epclusa treatment! Before I started treatment my viral load was 5,740,000. After 4 weeks of treatment it was down to 79! My liver enzymes are normal now. I struggled for about a week (week 9) with stomach problems, headaches and joint pain. I had stated previously I was Genotype 2 (B) and was diagnosed in 2005. Had 2 healthy kids and I am looking forward to kicking Hep c and my stage 2 Fibrosis. I have a new lease on life and I have a good feeling about curing this virus and watching my kids grow up. Stay positive, eat right and drink your water!"

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  • Tay
  • Taken for 1 to 6 months
  • November 7, 2019

For Hepatitis C "I am on month two. It has been very rough. A lot of nausea, diarrhea, night sweats, flu like symptoms, insomnia, chest pain, blisters on the inside of my mouth, itchy skin, hot flashes...it hasn't gotten any better. I am forever grateful tho. I am diagnosed with genotype 3A. I am still in F1 but almost F2 (mild scarring) I was denied treatment for 4 years or so and they finally approved me. I don't care what I go thru now as long as I am hep c free. My last labs are almost clear of hep c. Keep fighting!!!"

10 / 10
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27 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.