Florbetapir F 18 Dosage

Medically reviewed by Drugs.com. Last updated on Sep 27, 2023.

Usual Adult Dose for:

Positron Emission Tomography Imaging

Additional dosage information:

Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments

Usual Adult Dose for Positron Emission Tomography Imaging

370 MBq (10 mCi), maximum 50 microgram mass dose, intravenously as a single bolus in a total volume of 10 mL or less

Comments: The injection should be followed with an intravenous flush of 0.9% sterile sodium chloride.

Use: PET imaging of the brain to estimate beta-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline.

Renal Dose Adjustments

Data not available.

Liver Dose Adjustments

Data not available.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available.

Other Comments

Administration advice:

Use aseptic technique and radiation shielding to withdraw drug solution.
Assay the dose in a suitable dose calibrator prior to administration.
Inject florbetapir F-18 through a short intravenous catheter (approximately 1.5 inches or less) to minimize the potential for adsorption of the drug to the catheter. Portions of the drug may adhere to longer catheters.

General:

Florbetapir F-18 is a radioactive drug and should be handled with appropriate safety measures to minimize radiation exposure during administration.
Use waterproof gloves and effective shielding, including syringe shields when handling this drug.