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Iopamidol Injection Shortage

Last Updated: May 4, 2024
Status: Current

Products Affected - Description
    • Isovue Multipack-250 solution for injection, Bracco Diagnostics, 51%, 200 mL bulk glass bottle, 10 count, NDC 00270-1317-41 - discontinued
    • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1315-41 - discontinued
    • Isovue Multipack-300 solution for injection, Bracco Diagnostics, 61%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1315-98 - discontinued
    • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 200 mL pharmacy bulk glass bottle, 10 count, NDC 00270-1316-41 - discontinued
    • Isovue Multipack-370 solution for injection, Bracco Diagnostics, 76%, 500 mL pharmacy bulk glass bottle, 6 count, NDC 00270-1316-98 - discontinued
    • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 50 mL single dose vial, 10 count, NDC 00270-1314-30 - discontinued
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 100 mL single dose glass bottle, 10 count, NDC 00270-1317-02
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 150 mL single dose glass bottle, 10 count, NDC 00270-1317-09 - discontinued
    • Isovue-250 solution for injection, Bracco Diagnostics, 51%, 50 mL single dose vial, 10 count, NDC 00270-1317-05 - discontinued
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 100 mL single dose glass bottle, 10 count, NDC 00270-1315-35
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1315-45
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 50 mL single dose vial, 10 count, NDC 00270-1315-30 - discontinued
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1315-95
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 75 mL single dose glass bottle, 10 count, NDC 00270-1315-47 - discontinued
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 100 mL single dose glass bottle, 10 count, NDC 00270-1316-35
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 125 mL single dose glass bottle, 10 count, NDC 00270-1316-04 - discontinued
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 150 mL single dose glass bottle, 10 count, NDC 00270-1316-37 - discontinued
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 200 mL imaging bulk package glass bottle, 10 count, NDC 00270-1316-45
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 50 mL single dose vial, 10 count, NDC 00270-1316-30 - discontinued
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 500 mL imaging bulk package glass bottle, 6 count, NDC 00270-1316-95
    • Isovue-370 solution for injection, Bracco Diagnostics, 76%, 75 mL single dose glass bottle, 10 count, NDC 00270-1316-52 - discontinued
    • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 20 mL single dose vial, 10 count, NDC 00270-1411-25 - discontinued
Reason for the Shortage
    • Bracco has Isovue on shortage due to increased demand.
    • Bracco discontinued Isovue-M 200 (41%) in 20 mL vials in April 2022. Isovue 370 (76%) in 150 mL bottles were discontinued in November 2022.
Available Products
    • Isovue-200 solution for injection, Bracco Diagnostics, 41%, 200 mL single dose glass bottle, 10 count, NDC 00270-1314-15
    • Isovue-300 solution for injection, Bracco Diagnostics, 61%, 30 mL single dose vial, 10 count, NDC 00270-1315-25
    • Isovue-M 200 intrathecal solution for injection, Bracco Diagnostics, 41%, 10 mL single dose vial, 10 count, NDC 00270-1411-11
    • Isovue-M 300 intrathecal solution for injection, Bracco Diagnostics, 61%, 15 mL single dose vial, 10 count, NDC 00270-1412-15
    • Iopamidol solution for injection, Slate Run Pharmaceuticals, 41%, 10 mL vial, 10 count, NDC 70436-0124-82
    • Iopamidol solution for injection, Slate Run Pharmaceuticals, 41%, 20 mL vial, 10 count, NDC 70436-0124-52
    • Iopamidol solution for injection, Slate Run Pharmaceuticals, 61%, 15 mL vial, 10 count, NDC 70436-0126-82

Estimated Resupply Dates

    • Bracco has most Isovue-300 and Isovue-370 presentations on allocation to existing customers. Isovue-250 in 100 mL bottles are on back order and the company estimates a release date of early-to-mid-May 2024.

Updated

Updated May 4, 2024 by Elyse MacDonald, PharmD, MS, BCPS. Created November 21, 2018 by Stephen Andrews, PharmD, BCPS, CPPS, Drug Information Specialist. © 2024, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

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