Smoking Increases Risk for Adverse Cardiovascular Outcomes After PCI
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Sept. 27, 2023 -- For patients undergoing percutaneous coronary intervention (PCI), smoking is associated with an increased risk for adverse cardiovascular outcomes, according to a study published online Sept. 27 in the European Heart Journal.
Using a nationwide database from the Korean National Health Insurance System, You-Jeong Ki, M.D., from the Uijeongbu Eulji Medical Center in the South Korea, and colleagues examined the impact of smoking and its cessation after PCI on cardiovascular outcomes among 74,471 patients undergoing PCI between 2009 and 2016. Participants were classified as nonsmokers, ex-smokers, or current smokers, depending on their status at the first health checkup within one year following PCI.
The researchers found that current smokers had a 19.8 percent higher rate of major adverse cardiovascular and cerebrovascular events (MACCE) than nonsmokers during 4.0 years of follow-up (adjusted hazard ratio, 1.198), while the rate was comparable for ex-smokers and nonsmokers. The effects of smoking cessation were analyzed among 31,887 patients with both pre- and post-PCI health check-up data. For those who stopped smoking after PCI, the rate of MACCE was comparable for quitters with cumulative smoking exposure of <20 pack-years (PYs) and persistent nonsmokers. However, quitters with cumulative exposure of ≥20 PYs had a rate that was comparable with that of persistent smokers (adjusted hazard ratios, 1.206 for 20 to 30 PYs; 1.227 for ≥30 PYs; and 1.223 for persistent smokers compared with persistent nonsmokers).
"Smoking cessation as early as possible would be recommended as a fundamental measure of better clinical outcomes for patients undergoing PCI," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2023
Read this next
Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM
FRIDAY, May 31, 2024 -- For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from...
DNA Methylation-Based Epigenetic Age Mediates Link Between LE8 Score, CVD
WEDNESDAY, May 29, 2024 -- The associations between Life's Essential 8 (LE8) and cardiovascular health are mediated by DNA methylation-based epigenetic age, according to a study...
Parental E-Cigarette Use Linked to Increase in Pediatric Atopic Dermatitis
TUESDAY, May 28, 2024 -- Parental electronic cigarette use is associated with increased odds of pediatric atopic dermatitis (AD), according to a research letter published online...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.