Titanium 5

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza₃-Respiratory Syncytial Virus Vaccine

Modified Live Virus

from the Signature cell line^®

Titanium 5 Indications

This product has been shown to be effective for the vaccination of healthy cattle against infectious bovine rhinotracheitis virus (IBR), bovine virus diarrhea virus Type I (BVD), bovine virus diarrhea virus Type II (BVD), bovine parainfluenza₃ virus (PI₃) and bovine respiratory syncytial virus (BRSV). The duration of immunity has not been determined. This product was licensed prior to the requirement to establish a minimum age for use. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

Titanium 5 may be used in pregnant cows and calves nursing pregnant cows provided they were vaccinated, 30 to 60 days pre-breeding, with Titanium 3, Titanium 3 LP, Titanium 3 + BRSV, Titanium 3 + BRSV LP, Titanium 4, Titanium 4 L5, Titanium 5, or Titanium 5 L5 HB.

This product contains BVD Type I and BVD Type II.

DIRECTIONS AND DOSAGE: Rehydrate the desiccated vial with accompanying diluent and shake well. Inject 2 mL subcutaneously using aseptic technique, followed by a second dose of monovalent bovine respiratory syncytial virus vaccine (Titanium BRSV) to be given 14-28 days after the first dose. The need for annual booster vaccinations has not been established for this product. The presence of maternal antibody is known to interfere with the development of active immunity in calves and additional boosters will be required in most young animals. For advice on revaccination frequency, consult your veterinarian. Do not mix with other products, except as specified on the label.

Titanium 5 Caution

Fetal health risks associated with the vaccination of pregnant animals with this vaccine cannot be unequivocally determined during clinical trials conducted for licensure. Appropriate strategies to address the risks associated with vaccine use in pregnant animals should be discussed with a veterinarian. Failure to follow label directions may result in abortions. Store at 35-46°F (2-8°C). DO NOT FREEZE. Use entire contents when first opened. Do not vaccinate within 21 days of slaughter. In case of human exposure, contact a physician. Inactivate unused contents before disposal. Allergic reactions may follow the use of vaccines; ANTIDOTE: Epinephrine.

FOR USE IN ANIMALS ONLY

Manufactured by:

Diamond Animal Health, Inc., Des Moines, Iowa 50327 U.S.A.

U.S. Veterinary License No. 213

Product Code No. 1181.20

Distributed by:

Elanco US, Inc., Greenfield, IN 46140 U.S.A.

1-800-428-4441

CPN: 1131137.0